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OBJECTIVE
To be professional and progressive Bio-organic Medicinal and Pharmaceutical chemist through continuous learning and implementing new ideas through my dedication, hard work and knowledge in the rational drug design, accepting new challenges for the development of new procedures in the field of Drug Design and Drug Discovery.
PROFESSIONAL RESEARCH EXPERIENCE
Post Doctoral Associate 2009-Present
College of Pharmacy, The University of Georgia- Athens, GA, USA
- Designing of anti-HIV, anti-influenza and toxoplasma gondii inhinitors
- Molecular modeling studies on anti-HIV, anti-influenza and toxoplasma gondii inhinitors
- Synthesis of anti-influenza and toxoplasma gondii nucleosides inhibitors (NRTIs)
- Design and synthesis of anti-HIV prodrug
Post Doctoral Research Fellow 2007-2009
City of Hope Beckmann Research Institute- Duarte, CA, USA
- Peptide library design
- Synthesis of peptide library on peptide synthesizer
- HPLC purification of peptide library
- MALDI-TOF characterization
- Synthesis of Fusion peptides
- Synthesis of ODN-peptide conjugates
- Preparation of Microsphere of fusion peptide, fusion peptide+DNA etc
Research Fellow 2002-2007
Central Drug Research Institute, Lucknow, UP 226001, India
- Development of an efficient solution phase synthesis of 4-thiazolidinone and 4-metathiazanones.
- Development of an efficient solid phase synthesis of 4-thiazolidinone and 4-metathiazanones.
- Application of various two-dimentional and three-dimensional quantitative structure-activity relationship (3D-QSAR) and molecular modeling techniques for the development of theoretical models for anti-HIV inhibitory agents.
- Biological screening of the synthesized compounds as HIV-RT inhibitors.
- In vitro HIV-RT kit basedscreening of anti-HIV agents
- In vitro Anti-HIV-1 RT activity in MT-4 and CEM cells
Project Chemist 2001-2002
Zydus-Cadila Research Centre-Ahmedabad-380015, India
- Development of novel route for Clopidogrel Bisulphate
- Scale up of Clopidogrel Bisulphate from basic scale to large scale (55kg)
Project Trainee 2000
National Institute of Pharmaceutical Education and Research (NIPER) Chandigarh, India
- “Synthesis of some industrially important drug intermediates ”
Part A. Conversion of Threo to Erythro Mefloquine Enantiomer
Part B. Synthesis of trans-(-)-3-(4-methoxyphenyl) glycidic ester
- Spectroscopic characterization of synthesized compounds
Experience in Organic synthesis
- Synthesis and characterization of aromatic heterocyclic scaffolds.
- Synthesis and characterization of nucleoside and its prodrug.
- Comfortable handling of milligram to multigram scale reactions.
- Proficient in using chemistry data base e.g. SciFinder, DiscoveryGate, web of science, ISIS, Medlabs etc.
- Expertise in peptide library designing and synthesis.
Instruments and Techniques
- Column Chromatography, Flash Chromatography, HPLC, Crystallization.
- 1D and 2D NMR, IR, Mass spectroscopy (ESI, MALDI-TOF), micro-analysis, X-ray analysis, Polarimetery.
- UV-vis; Fluorescence spectroscopy, DSC and TGA.
Communication Skills
For scientific publications, I have proficient experience in analyzing and technical writing of scientific results.
COMPUTATIONAL SOFTWARE AWARENESS
- Schrodinger suite 2009
- Tripos: Sybyl7.0
- CCG: Molecular Operating Environment (MOE 2003-04)
- Build-QSAR
- Combinatorial Protocol for Multiple Linear Regression (CP-MLR) Analysis
PROFESSIONAL MEMBERSHIPS
- Recipient of Dr. M.M. Dhar Memorial Prize-2005 for Best Thesis in Chemical Sciences by Central Drug Research Institute (CDRI), Lucknow, U.P., India
- Recipient of Top Cited Author 2005-2008 Certificate from ACS National Meeting in Philadelphia
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4 comments
vinay
July 29, 2011 at 11:19 am (UTC 0) Link to this comment
nice website….
admin
December 21, 2011 at 12:30 am (UTC 0) Link to this comment
Thanks Dear!
prashant
December 8, 2011 at 12:54 am (UTC 0) Link to this comment
Nice work! I wish I had one too.
See you sometime on coffee table!
Prashant
admin
December 21, 2011 at 12:30 am (UTC 0) Link to this comment
Thanks Dear! Ya sure I am always ready for chit-chat at coffee table.
Rawal